Junior Algorithm Developer Intern

• 19 September 2026
• 100%
• Indefinite duration
• Rolle

What if your internship project could influence the detection of genomic variants in real clinical technology?

At SOPHiA GENETICS, we are building the future of AI-assisted and data-driven medicine. Our technology helps healthcare professionals understand complex multimodal data, with the ambition of improving outcomes for patients with cancer and rare diseases.

This mission raises complex scientific and computational questions.

One of them is this: how can we ensure that our algorithms identify complex genomic variants with the greatest possible accuracy and efficiency?

That is where you come in.

Join our Data Science - Algorithm Development team in Rolle, Switzerland, for a six-month internship as a Junior Algorithm Developer.

You will work on a real challenge within our Whole Genome Sequencing (WGS) product: evaluating our internal structural variant (SV) calling solutions by comparing them to state-of-the-art external tools for germline variant calling.

The evidence you generate will help our team understand where different approaches perform well, where they do not, and to guide decisions on the evolution of our WGS technology.

You will directly handle genomic data, algorithms, and production-scale computing infrastructure.

Your missions will be:

• Build the reference. Install and run external WGS variant calling pipelines on the SOPHiA GENETICS computing infrastructure and create a reproducible environment for comparison.
• Put the tools to the test. Evaluate the accuracy and execution time of germline variant calling using our data and reference sets.
• Go beyond "which tool is better?". Compare external approaches with our internal SV calling solutions and analyze where and why they differ.
• Transform data into decisions. Translate your findings into evidence-based recommendations to improve the strategy, design, implementation, and performance of SV calling in our germline WGS products.
• Make your work visible. Present your findings to team and department colleagues, including management.

Requirements

You may be studying bioinformatics, computational biology, computer science, statistics, or a related field. It is not necessary to know everything about structural variant calling upon your arrival - we value your way of thinking as much as your learning speed.

This internship will likely appeal to you if:

• You enjoy exploring data and asking "why?", rather than stopping as soon as you have a result.
• Statistics and probability speak to you, and you enjoy using them to solve concrete problems.
• You are comfortable with the UNIX command line and have some experience analyzing large datasets.
• You have experience with Python or statistical libraries - or are motivated to deepen these skills.
• You are curious about genomics; knowledge of structural variant calling, WGS, or VCF is a plus but not a prerequisite.
• You have a scientific mind: you are ready to ask questions that may seem naive, test hypotheses, and report what the data actually shows, even if the answer is not the expected one.
• You communicate and collaborate well with others and are comfortable working in English.

Benefits

In six months, we want you to leave with much more knowledge than when you arrived.

You will learn how an end-to-end NGS data analysis workflow is built and used in an industrial setting, develop a deep understanding of state-of-the-art structural variant calling tools and algorithms, and acquire practical experience in designing a rigorous benchmarking study.

More importantly, you will see how scientific evidence becomes a product decision.

You will work in an environment where genomics, data science, AI, and cloud technologies converge, alongside people who solve these problems every day.

Company-wide events and activities - participate in company events, general assemblies, internal initiatives, and social activities with the rest of our employees.

All our internships and apprenticeships are paid, with compensation aligned with local market practices and standards.

Location: Rolle, Switzerland

Start: As soon as possible

Contract type: Internship contract, full-time, 6 months.

Apply with your CV and any additional information you would like us to take into account.

Selected candidates will meet members of our talent management team, the recruiting manager, as well as relevant colleagues and stakeholders during the interview process.

English is our primary working language, please submit your CV in English.